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Phenomenex adds polar, mixed-mode selectivities for column line

Luna and Luna Omega Columns new selectivities for UHPLC

Phenomenex has launched mixed-mode selectivities and particle sizes for UHPLC, HPLC and preparative work in the Luna column range.

Luna Omega columns are suited for applications including drug discovery and development, food contaminant analysis and environmental testing.

The first is the Luna Omega Polar C18 stationary phase - selectivity on a silica particle that delivers a wide elution window and high retention for polar and nonpolar analytes.

It is aqueous-stable due to a polar-modified surface, providing flexibility in solvent and gradient system selection needed to achieve desired polar/non polar analyte separation.

The Luna Omega Polar C18 is in a high-performance 1.6µm particle for UHPLC instruments as well as a low-pressure 5µm particle for scalability to analytical HPLC or preparative work. The 5µm particle is available in Phenomenex's Axia-packed preparative columns.

Phenomenex also introduced the aqueous-stable Luna Omega PS C18 that delivers two separation mechanisms at once. The particle surface of the PS C18 contains a positive charge that facilitates acidic compound retention through ionic interaction, while the C18 ligand delivers general reversed-phase retention.

This mixed-mode selectivity is for greater separation between mixtures of compounds that have varying functional groups, such as peptides, pesticides or metabolite profiles.

Simon Lomas, strategic marketing manager for Phenomenex, said: "The recent expansion of this column family with novel Luna Omega silica particle technology and mixed-mode polar stationary phases has enabled us to bring the Luna legacy to the UHPLC world."

Phenomenex also unveiled the Kinetex 2.6 µm Polar C18. This stationary phase combines C18 ligands with a polar-modified surface to enable superior retention of polar and nonpolar compounds while ensuring full aqueous stability.

Key applications for this dual selectivity include pesticide screening in food, testing of emerging environmental contaminants and drug analysis in pharmaceutical discovery.

Incorporating the Kinetex Core-Shell Technology, the 2.6 µm Polar C18 particle size is for HPLC systems and could increase resolution, sensitivity and separation speed.

Lomas added: "This new selectivity greatly enhances polar/nonpolar retention compared to traditional alkyl phases and gives customers a versatile product with which they can start reversed phase method development."

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