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Advion launches liquid chromatography systems

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Advion has released ultra-high performance liquid chromatography (UHPLC) and HPLC systems to add to techniques for organic and analytical chemists.

Coupled with the expression compact mass spectrometer (CMS), they help chemists with UHPLC/CMS and HPLC/CMS analysis.

Building on sample introduction techniques including the Plate Express TLC plate reader, the ASAP liquids and solids probe, the iASAP probe for air-sensitive compounds and the volatile APCI source, the UHPLC/CMS and HPLC/CMS provides another technique for organic and analytical chemists.

David Patteson, Advion CEO, said it pioneered systems for direct mass analysis of solids and liquids, and integrated TLC/CMS plate analysis.

“With the addition of the UHPLC/CMS and HPLC/CMS systems, a decades-old industry-accepted technique will operate in synergy with our user friendly compact mass spec software suite that bench chemists have come to rely upon.”

Advion develops, manufactures and supports mass spectrometers, chip-based ion sources, and consumables for life science and related industries.

The firm has also released Peak Express software, available with the expression CMS, for compound ID and reaction monitoring.

It introduces a patent-pending development in novel mass spectrum display, available only in the Advion Peak Express software suite: The Delta Spectrum (ΔS), which looks beyond chemical noise and detects the smallest peaks without the user knowing the product ion mass in advance.

Peak Express can be used with any technique that generates a peak, e.g. HPLC/CMS, TLC/CMS, Flash/CMS, and FIA in real time and for later data processing.

Patteson said there is a need for reaction monitoring, compound identification and purification in environments where high levels of contaminants and chemical noise are present.

“Peak Express is like having the expertise of a dedicated mass spectroscopist, digging deep in to the data to find small, unknown peaks that would otherwise have gone undetected, or reveal the detail that would have otherwise been missed. The chemist can “see more” as peaks are revealed and chemical noise is eliminated from the spectrum.”

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